Our Science

Our Pipeline

AERASYN's pipeline includes two lead buccal programs and two additional programs exploring modified molecular and oral-formulation profiles.

Lead programs

Lead · Preclinical

Buccal Ibogaine

Evaluating whether precision formulation and buccal administration can create a more controllable ibogaine exposure profile.

Research context
Substance-use and trauma-associated disorders
Scientific approach
Buccal formulation + route
Development focus
PK, bioavailability, safety and tolerability

Relevant IP: Therapeutic + Delivery + Manufacturing

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Lead · Preclinical

Buccal 5-MeO-DMT

Investigating whether buccal formulation can support rapid, consistent absorption and a predictable short-duration exposure profile.

Research context
Neuropsychiatric therapeutic research
Scientific approach
Buccal formulation + route
Development focus
Comparative PK, dose consistency and tolerability

Relevant IP: Therapeutic + Delivery

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Additional programs

Distinct programs with focused scientific questions.

These programs extend the pipeline beyond the two lead buccal assets while remaining early and hypothesis-driven.

Additional · Preclinical research

PEGylated Synthetic Psilocin Analogs

Three proprietary analogs are being explored for modified pharmacokinetic and half-life characteristics in non-hallucinogenic preclinical models.

Research context
Neuroinflammation and neurodegeneration
Scientific approach
PEGylated synthetic analog design
Development focus
PK profile, half-life and pharmacology

Relevant IP: Discovery + Therapeutic

Additional · Early discovery

Oral Bufotenin

Exploratory work around an oral formulation and the bufotenin tryptamine scaffold for neuropsychiatric research.

Research context
Exploratory neuropsychiatric research
Scientific approach
Oral formulation exploration
Development focus
Formulation, exposure and candidate characterization

Relevant IP: Therapeutic + Delivery

Development stages

A concise view of the current pipeline.

Buccal IbogaineLead programPreclinical
Buccal 5-MeO-DMTLead programPreclinical
PEGylated Synthetic Psilocin AnalogsAdditional programPreclinical research
Oral BufoteninAdditional programEarly discovery

Review the discovery, therapeutic, delivery and process coverage supporting the pipeline.

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